ORIGINAL ARTICLE
Year : 2019  |  Volume : 2 |  Issue : 2 |  Page : 1-5 |  DOI : https://doi.org/10.46319/RJMAHS.2019.v02i02.001

Lupus nephritis: clinico-biochemical profile of cases from a tertiary care renal referral centre.

Mythri KM¹, Kowsalya R^2*
1Associate Professor, Department of Microbiology, ² Associate Professor, Department of Biochemistry, Instiute of Nephro Urology, Victoria Hospital campus, Bangalore-560002.

*Corresponding author:
Dr. Kowsalya R, MD, Biochemistry Associate professor of Biochemistry Instiute of Nephro Urology, Victoria Hospital campus Bangalore-560002.
E-mail: r.kowsalya@gmail.com

Abstract
Introduction: Systemic lupus erythematosis is a multi-systemic disorder where renal impairemnet is seen and remains the most dangerous life threatening complication. Renal manifestations are highly pleomorphic and patients present with varied symptoms from asymptomatic proteinuria to renal insufficiency warranting dialysis. Material and Methods: We describe spectrum of 50 biopsy proven cases of lupus nephritis patients at our exclusive tertiary care renal referral centre. Results: The study consisted of 50 patients, 43 females and 7 males with mean age 30.6 ± 11.6 years at time of presentation. Clinically the frequent presenting symptoms was of nephrotic syndrome followed by renal insufficiency. Five cases were adolescents aged between 12 and 17 years and one patient succumbed highlighting that lupus nephritis is severe in childhood. Conclusion: Lupus nephritis is one of the important causes of morbidity and mortality in patients with SLE. Thus with all the clinical and therapeutic constraints the lupus nephritis management still remains a challenge.
Keywords: Lupus, nephritis, renal