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Year : 2021 |  Volume : 4 |  Issue : 2|  Page : 1-5


A clinical study on ocular surface dysfunction and tear film abnormalities in patients with diabetes mellitus
FarandeSamruddhi Diliprao1*, Lokesh H M2
1*Postgraduate Student, 2 Professor, Department of Ophthalmology, Sri Siddhartha Medical College, SSAHE Tumkur, Karnataka India

* Address for Correspondence:
Dr. FarandeSamruddhi Diliprao, 3rd year PG, Dept of Ophthalmology Sri Siddhartha Medical College, SSAHE Tumkur Karnataka India. Email: samruddhi1210@gmail.com

Abstract
Background: Diabetes is a leading cause of ocular morbidity which is progressive and preventable with early diagnosis and treatment. It is a one of the important cause of avoidable blindness in the developed as well as developing countries. Ocular complications of diabetes mellitus include diabetic retinopathy, papillopathy, cataract, glaucoma, and ocular surface disease. Among these, diabetic retinopathy and diabetic cataract are major complications of type 2 diabetes mellitus. In the progression of disease, duration of  type II diabetes mellitus , blood sugar control, already existing hypertension, dyslipidemia, nephropathy and also anemia play an important role. In type II diabetes mellitus patients, ocular surface disorderlike dry eye has been noticed recently.  Type 2 Diabetes and dry eye disorder has found  to have a noticeable effect on  patient's quality of life  which is proven in multiple studies. Objective:To compare the tear film changes and ocular surface dysfunction in type 2 diabetes mellitus patients with non -diabetic patients. Methodology: A cross sectional study was conducted in Department of Ophthalmology at a Tertiary Care centre in Tumkur.  A total of 60 study subjects with type 2 diabetes mellitus patients and 60 non diabetic patients coming to ophthalmology OPD were selected for the purpose of study by convenient sampling technique. Results: Age and gender was matched between diabetics and non diabetics, Among Diabetics mean Schirmer'sTest was 9.43 ± 3.41 mm and among non-diabetics mean Schirmer's Test was 14.20 ± 2.71 mm. There was significant decrease in Schirmer'sTest among diabetics as compared to non diabetics. Among Diabetics mean TBUT was 7.60 ± 2.63 Seconds and among non-diabetics was 10.67 ± 2.11 seconds. There was significant difference in TBUT between two groups. Conclusion: The study concluded that the decreased formation of tear film and the MGD findings with Conjunctival staining was found to be more among the diabetic study population than those neither who nor non diabetic. 
Keywords: Tear film, Ocular surface dysfunction, Diabetes mellitus


E-ISSN : 2582-080X |


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An official peer reviewed publication of
Sri Siddhartha Medical College & Research Centre
Constituent College of Sri Siddhartha Academy of Higher Education
(Deemed to be University u/s 3 of UGC Act, 1956)
Accredited 'A' Grade by NAAC
Tumakuru, Karnataka, India. 572107


Research Journal of Medical and Allied Health Sciences is a medium for the advancement of scientific knowledge in all the branches of Medicine and Allied Sciences and publication of scientific research in these fields. The scope of the journal covers basic medical sciences, medicine and allied specialities, surgery and allied specialities, dentistry, nursing, pharmacy, biotechnology, public health and other branches of the allied health sciences. This journal is indexed with Advanced Science Index(ASI), National Science Library and Open J Gate.