Year : 2020 | Volume : 3 | Issue : 2 | Page : 1 | DOI : https://DOI-10.46319/RJMAHS.2020.v03i02.001
Plateletcrit - An important indicator of hypertension induced organ damage
Swathy Shanker1, Niranjana Murthy B2
1 Postgraduate, 2 Professor & Head, Department of Pathology,
Sri Siddhartha Medical College & Research Centre, Tumakuru,
Sri Siddhartha Academy of Higher Education, Tumakuru.
Background: Hypertension being a major health problem worldwide, has been found to result in end-organ damage. Hypertensive patients have deranged haematological parameters, which in turn have been studied to be the cause of this outcome. Previous studies have evaluated the increase in haematocrit and RBC count in hypertensive patients. Hypertension related organ damage has a positive correlation with platelet activation. Variation in values of platelet indices have been reported as indicators of hypertension induced organ damage. We aim to assess the haematological parameters of individuals with hypertension and to compare the results with the haematological parameters of normotensive individuals and also highlight the parameter which can give an indication of the extent of endothelial damage. Material and Methods: This retrospective study includes patients chosen from medical records who had presented to Department of General Medicine, Sri Siddhartha Medical College for a period of 2 months and met the criteria to be included in the hypertensive group. A total of 60 patients' records were collected. 60 normotensive individuals were also chosen similarly from medical records of patients admitted in department of medicine and surgery, Sri Siddhartha Medical College during the same time period. Complete blood count reports of the patients were analysed. Results: The mean values of most haematological parameters showed higher values among hypertensive subjects compared to the normotensive group, with the exception of Mean Corpuscular Volume (MCV) which showed no variation among the two groups. Conclusion: The role of plateletcrit as a significant parameter in analysis of hypertension is understood and combination of haematocrit with plateletcrit values would be a better indicator of hypertension induced organ damage.
Keywords: Plateletcrit (PCT), Hypertension (HT), Hematocrit (HCT)
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Sri Siddhartha Medical College & Research Centre
Constituent College of Sri Siddhartha Academy of Higher Education
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Tumakuru, Karnataka, India. 572107
Research Journal of Medical and Allied Health Sciences is a medium for the advancement of scientific knowledge in all the branches of Medicine and Allied Sciences and publication of scientific research in these fields. The scope of the journal covers basic medical sciences, medicine and allied specialities, surgery and allied specialities, dentistry, nursing, pharmacy, biotechnology, public health and other branches of the allied health sciences. This journal is indexed with Advanced Science Index(ASI), National Science Library and Open J Gate.